Connect with us


Vaccine For Covid-19 Could Get Seriously Delayed As New Strain Detected In India



A new mutation of coronavirus sampled by the National Institute of Virology from a patient from Kerala, India has the potential to upend all the research performed by scientists and deal a massive blow to the development of COVID-19 vaccine.

Israel The Best, India Surprisingly ‘Very Good’ For Handling Covid-19 Pandemic: Research

A new study published by researchers from Taiwan and Australia said that the new mutation leads to a “weaker receptor binding capability” in the novel coronavirus, which is a proof that change has occurred in the part of the spike protein that allows the virus to bind with human cells.


With the new mutation, the scientific research done could prove futile as scientists were working on creating antibodies for ACE2 cells as the novel coronavirus had been targeting this particular receptor cells.

3265 People Died In Karachi in 49 Days; Official Death Toll Of Pakistan At 137

The antibodies are produced inside the human body in response to a vaccine or an infection and work by binding themselves to specific spots on a virus called an antigen. If random viral mutations alter the shape of an antigen, it can make a vaccine less effective against the virus.

Most of the research for developing a vaccine has been aimed at stopping the action of the viral spike (S) protein that the virus uses to enter human cells, where it replicates to cause infection. “The observation of this study raised the alarm that Sars-CoV-2 mutation with varied epitope [something an antibody attaches itself to] profile could arise at any time,” Wei-Lung Wang from the National Changhua University of Education in Taiwan, and his collaborators from Murdoch University in Australia wrote in a paper released on preprint review site on Saturday, April 11.

Diplomacy or Indian Army – What’s The Way Forward To Deepening Crisis In The Rakhine State Of Myanmar?

“[This] means the current vaccine development against Sars-CoV-2 is at a great risk of becoming futile,” they added, reports the South China Morning Post (SCMP). The findings of the study are yet to be peer-reviewed and will need further verification.

There is also a possibility that the mutation was caused by a technical error during the sequencing process and there is also a chance that the results produced by the computer simulation were misleading according to a researcher who spoke to SCMP on the condition of anonymity.

How India Is Winning Hearts, Minds & Money Via A Simple Anti-Malarial Drug?

The researchers said that they had identified a mutation that led to weaker receptor binding capability, from a Sars-CoV-2 sample collected on 27th January 2020 from India. The study found that the mutation occurred in the spike protein’s receptor-binding domain (RBD) which as per computer simulations showed it could remove a hydrogen bond from the spike protein which is essential for the virus to bind itself to ACE2 or angiotensin-converting enzyme-2, which is found in the lungs and other organs.

A Hindustan Times report quoted Dr. T Jacob John, professor emeritus and former head of virology at Christian Medical College, Vellore, Tamil Nadu saying that the lower receptor fit may make the virus less efficient in transmission, but then it is equally important to watch out for a change in virulence also.

But if the results are indeed accurate, they will hinder the creation of a long-lasting vaccine that is already in the clinical trial stage in China and the USA.

Kashmir Critics – Turkey & Malaysia Request India For HCQ Drug For Treating Covid-19

All viruses evolve over time, accumulating mutations as they replicate imperfectly inside a host’s cells. According to scientists, the genetic structure of the new coronavirus looks pretty much the same everywhere and there is no evidence suggesting that some strains are deadlier than others.

However, some researchers speculate that sampled and sequenced strains are just the tip of the iceberg and there may be newer mutations that would require newer vaccines.




Expert Reviews3 hours ago

Why China Desperately Needs Pakistan For Its ‘Cyber-Warfare’ Against India?

OPED: While tensions between India and China continue to mount and the disengagement process light-years away, Indian media reports claim...

Featured8 hours ago

From Afghanistan To Syria – This Is How Rafale Jets Have Dominated Skies Without Ever Being Shot-Down

Produced by Dassault Aviation, Rafales jets were first delivered to the French Navy in December 2000. The jets were part...

Pakistan-Turkey-Relations Pakistan-Turkey-Relations
Expert Reviews13 hours ago

China, Pakistan Want Turkey To Replace Saudi Arabia As The Leader Of Islamic World?

In recent years, Turkey has been vehemently fighting for the leadership role in the Islamic world. The transformation of the...

ISIS-Pakistan ISIS-Pakistan
Featured1 day ago

ISIS Attacks Afghanistan Prison; 20 People Killed, More Feared Dead

At least 20 people have been killed in fighting between security forces and ISIS gunmen raiding an Afghan jail, officials...

uae-nuclear-plant uae-nuclear-plant
Featured1 day ago

Can Israel Bomb Arab World’s First Nuclear Plant In The UAE?

Israel has been actively involved in maintaining its regional nuclear superiority with two key strategies: developing nuclear and other weapons...

Sikhs-in-Afghanistan Sikhs-in-Afghanistan
Featured2 days ago

Afghanistan: Hundreds of Taliban Prisoners Freed By Afghan Government

A rare ceasefire between the Taliban and Afghan government appeared to hold for the third and final day on Sunday,...

rafale-jets rafale-jets
Featured3 days ago

No Buyers For Rafale Jets: Why Almost Every Country Dumped French Rafales Except India?

The Rafale is one of the most expensive aircraft in the international market. India's deal of 36 jets is worth...

Americas3 days ago

From Indian Border To South China Sea, Chinese Air Force (PLAAF) Ups The Ante With H-6 Bombers

The H-6J is an upgraded variant of the decades-old H-6, a large bomber platform which first flew almost 60 years...

Asia Pacific3 days ago

Chinese Navy Installs New Turbo Generators to Power ‘Electromagnetic Railguns’ On It Warships

The Chinese Navy (People’s Liberation Army Navy) has installed new turbo generators on its warships. The decision to install the...

Featured4 days ago

Indian Army Fears A Repeat Of Siachen Conflict But This Time With China

During the Operation Meghdoot in Siachen in 1984, the Indian Army kept a close watch on suppliers of Arctic gear...